Sapala Organics

Overview

Sapala Organics is a nucleic acid chemistry organization that describes itself as a CRO and CDMO in the nucleic acid space. Founded in 2005, it began as a partner to Japan's pharma industry. The company states that it is now a subsidiary of Cohance Lifesciences Limited.

Services

• Custom synthesis: specialized nucleic acid building blocks, heterocyclic compounds, drug delivery compounds, and tailored oligonucleotide synthesis using modified phosphoramidites.
• Contract development and manufacturing: solutions for drug development and delivery, with a focus on oligonucleotide-based therapies that target diseases at the genetic level.
• Analytical services: an analytical facility offering a range of orthogonal analytical techniques for customers from early R&D to pharma innovators.
• Engagement models: CRO on an FTE basis, CDMO on a fee-for-service (FFS) basis, analytical services, and customized models.

Focus areas

The site lists medicinal chemistry, carbohydrate chemistry, lipid and GalNAc chemistry, and fluorescent chemistry as chemistry areas. Its stated audiences include academia, biotech start-ups, oligo CDMOs, therapeutic companies, mRNA vaccine innovators, and sequencing technology makers.

Market position

The company states it has more than 100 years of combined leadership experience in nucleic acid chemistry and a portfolio aimed at next-generation oligonucleotide drugs and NCE programs. It also sells catalog products, including nucleoside and phosphoramidite derivatives, linkers and spacers, PEG derivatives, and miscellaneous products.