ProBioGen AG
30+ years of CDMO expertise in proteins, viral vectors, and vaccines. German quality.
Listed on cdmo.directory
ProBioGen is a fully integrated CDMO specializing in development and GMP manufacturing of therapeutic proteins, viral vectors, and vaccines, with proprietary platforms including CHO.RiGHT® for cell line development and AGE1.CR.pIX® for vaccine production. Headquartered in Berlin, Germany.
Modalities
Services
Indications
About this organization
Overview
ProBioGen AG is a contract development and manufacturing organization (CDMO) with over 25 years of operational experience specializing in biopharmaceuticals, viral vectors, and vaccines. The company operates two locations in Berlin, Germany, with more than 200 employees.
Core Capabilities
Protein & Antibody Services
- Cell Line Development: CHO.RiGHT® producer cell line platform enabling development from gene to fully characterized research cell bank within 15–18 weeks
- Process Development: Fed-batch bioreactor performance assessment and scalable manufacturing processes
- GMP Manufacturing: Robust, compliant production across multiple scales
- Analytical Services: Comprehensive quality analytics and bioassays for proteins and antibodies
- Glycoengineering: GlymaxX® platform for ADCC optimization and controlled fucosylation
- Biosimilars & Biobetters: Dedicated development pathways
Viral Vector & Vaccine Services
- AAV Production: End-to-end development and manufacturing
- Lentivirus Production: Lenti.RiGHT® proprietary packaging and producer cell line system delivering high titers and stable vectors
- Poxvirus Production: Including MVA-based platforms (MVA-CR19 vector platform)
- Producer Cell Line Development: AGE1.CR.pIX® duck suspension cell line for industrial GMP-compliant production in chemically-defined media; extensively tested against adventitious agents and used in clinical trials
- Quality Analytics: Release testing, stability studies, and bioassays
Proprietary Technologies
- CHO.RiGHT®: Expression platform for therapeutic proteins
- DirectedLuck®: Transposase-based integration system targeting epigenetic marks for stable, high-activity transgene integration
- GlymaxX®: Glycoengineering platform for antibody ADCC and fucosylation control
- Lenti.RiGHT®: Lentiviral vector production system
- AGE1.CR.pIX®: Designer cell line for vaccine and viral vector manufacturing
- MVA-CR19: Vector platform for vaccine development
Quality & Compliance
All services and technologies are embedded in a total quality management system ensuring compliance with international ISO and GMP standards (EMA/FDA). The company provides comprehensive regulatory support and formulation development services.
Certifications
Locations
Headquarters
Berlin · Berlin · Germany
Office
Berlin · Berlin · Germany
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